Consider the growth of enterobacter aerogenes in each of two independent chemostat operations, each of volume 500 L, each operating at steady state. Cell maintenance effects in each bioreactor are negligible, and product formation in each bioreactor is negligible. Growth of E, aerogenes in each bioreactor is limited by ammonium ion, such that
Mass transfer limitations in each bioreactor are negligible. Finally, in each bioreactor, the feed is sterile and inlet flow rates are identical with S0 = 4.8 g/L, but substrate conversions are not the same.
Now suppose cell maintenance effects are not negligible, such that maintenance is achieved entirely by endogenous metabolism, with Kd = 0.030 h-1.
Determine whether YX/S,obs in either bioreactor would be expected to change with a change in flow rate.
This question belongs to bioreactors in biotechnology and discusses about bioreactors and to determine YX/S,obs in a bioreactor cell maintenance effects are not negligible.
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