# Calculation of Difference Between New Drug for Heart Rate Reduction and Placebo

Question

Use the following description and table to answer the questions.
A pharmaceutical company wants to determine if there is a significant reduction in heart rate with their new drug, Clardozan, at the .01 level of significance. The researchers took a random sample of 30 adults and randomly selected each to receive either Clardozan or the placebo. Heart rates for each subject and treatment group are presented below; assume data are normally distributed with equal variances.

Subject    Clardozan Heart Rate    Subject    Placebo Heart Rate
1                     81                      2                   78
4                     60                      3                   88
7                     91                      5                   63
8                   103                      6                   56
10                     85                      9                   70
13                     88                     11                  77
14                     84                     12                  64
16                     60                     15                  48
17                     60                     18                  51
19                     72                     20                  52
23                     96                     21                  76
24                     75                     22                  80
26                     58                     25                  51
29                     70                     27                  66
30                     81                     28                  55

1.    What is the independent variable? What is the dependent variable? Why?
2.    What is the null hypothesis? What is the alternative hypothesis? Is this a one-tailed or a two-tailed test?
3.    What test statistic will you use? Why?
4.    What is the critical value? What is the value of the test statistic?
5.    Would you accept or reject the null hypothesis? Explain your conclusion in a 100 to 150 word summary.

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